Sindireva A. V., Maydanyuk G. A., Golubkina N. A.

Influence of selenium on the content of microelements in the liver of Wistar rats


The aim of this research is to evaluate the influence of selenium on the balance of microelements (i.e. Fe, Zn, Cu, Cr, Co, I, Mo) in the liver of Wistar rats. The subjects of research were as follows: liver of Wistar rats, microelements (Fe, Zn, Cu, Cr, Co, I, Mo). The experimental animals received a standard laboratory diet, for four months selenium solution in the form of Na2SiO3 was daily included into the diet of the experimental group “Selenium”. Liver was used as a material for studies. The physiological role of selenium is a subject of extensive scientific research. The main function of selenium is, first of all, its participation in antioxidant processes. Despite numerous studies confirming the need for selenium presence in the organism of animals and people, there is also a proven evidence of its toxicity when its concentration exceeds the maximum accepted levels. While the influence of selenium on plants has been studied thoroughly; the mechanism of this microelement influence on animal or human bodies requires additional study. The following data have been obtained: when the solution of Na2SiO3 is introduced into the body of animals, an increase in the content of the following microelements takes place, i.e. Co – 121.14%, I – 21.41%, Mn – 23.19%, Fe – 35.39%. The content of chrome has decreased by 55.43% as a result of selenium influence. The content of copper and zinc in the rat liver has not changed significantly under the influence of selenium.

About the autors:

Anna Vladimirovna Sindireva (1), Doctor of Biological Sciences, Professor; Grigoriy Alekseevich Maydanyuk (2), post-graduate at the Department of Ecology, Nature Management and Biology at the Faculty of Agrochemistry, Soil Science, Ecology, Environmental Engineering and Water Management; Nadezhda Aleksandrovna Golubkina (3), Doctor of Agricultural Sciences, Leading Researcher

Place of employment:

Tyumen state University, Institute of Earth Sciences (1); Omsk State Agrarian University named after P.A. Stolypin (2); Federal Scientific Center for Vegetable Growing (3)


e-mail: (1); e-mail: (2);

Key words:

selenium; macro and microelements; animal organism; liver